Metabolism of the plant growth regulator 2,3,5-triiodobenzoic acid in soybeans

✍ Scribed by L. A. Spitznagle; J. E. Christian; A. J. Ohlrogge

• Publisher: John Wiley and Sons
• Year: 1969
• Tongue: English
• Weight: 486 KB
• Volume: 58
• Category: Article
• ISSN: 0022-3549
• DOI: 10.1002/jps.2600581016

✦ Synopsis

lowed by a spontaneous change in its surface properties, could also account for some of the change observed following irradiation of chlorpromazine. The sulfoxide, at these concentration levels, would not be expected to contribute to this change.

Since all of these compounds are metabolites of chlorpromazine (7), it would appear that the accumulation in the skin of not only the parent compound, but, more importantly, of some of its metabolites, may be responsible for the reported phototoxic reactions. It would be interesting to determine whether a relationship exists between the level of chlorpromazine and its N-oxide in the skin and the incidence of phototoxicity.