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Metabolism of N‘ -Nitrosonornicotine Enantiomers by Cultured Rat Esophagus and in Vivo in Rats

✍ Scribed by McIntee, Edward J.; Hecht, Stephen S.


Book ID
125952493
Publisher
American Chemical Society
Year
2000
Tongue
English
Weight
102 KB
Volume
13
Category
Article
ISSN
0893-228X

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p -HYDROXYMETHAMPHETAMINE ENANTIOMER PHA
✍ A. HUTCHALEELAHA; M. MAYERSOHN 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 151 KB 👁 2 views

p-hydroxymethamphetamine (OHMAP) is one of the major metabolites of the widely abused drug methamphetamine (MAP). The demethylation of OHMAP to phydroxyamphetamine (OHAP) has been shown in vitro but has never been reported in vivo. The disposition kinetics as well as the metabolism of OHMAP was inve