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Metabolism of mono- and dichloro-dibenzo-p-dioxins byPhanerochaete chrysosporiumcytochromes P450

โœ Scribed by Noriyuki Kasai; Shin-ichi Ikushiro; Raku Shinkyo; Kaori Yasuda; Shinji Hirosue; Akira Arisawa; Hirofumi Ichinose; Hiroyuki Wariishi; Toshiyuki Sakaki


Publisher
Springer
Year
2010
Tongue
English
Weight
181 KB
Volume
86
Category
Article
ISSN
1432-0614

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Metabolism of polychlorinated dibenzo-p-
โœ Keke Hu; Nigel J. Bunce ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 121 KB ๐Ÿ‘ 1 views

The in vitro metabolism of several chlorinated dibenzo-p-dioxin congeners (PCDDs) was studied using rat liver microsomes as a source of CYP 1 enzymes. The reactions were kinetically first order in both enzyme and substrate and showed a general trend toward decreasing reactivity with increasing chlor