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Metabolism of 5′-ether prodrugs of 1-β-d-Arabinofuranosyl-E-5-(2-bromovinyl)uracil in rats

✍ Scribed by Noriyuki Ashida; Katsushi Ijichi; Yohko Watanabe; Haruhiko Machida


Book ID
115783589
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
530 KB
Volume
46
Category
Article
ISSN
0006-2952

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1 4 C-Labelled l-~-D-arabinofuranosyl-E-5-(2-bromovinyl)uracil (BV-araU) was synthesized in 26.6% radiochemical yield from 1-R-Darabinofuranosyl-5-formyluracil and '"C-labelled malonic acid for the purpose of the metabolic studies in animals.