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Metabolism of [3H] 17β-dihydroequilin and [3H] 17β-dihydroequilin sulfate in normal postmenopausal women

✍ Scribed by Bhagu R. Bhavnani; Anthony Cecutti; Duncan Wallace

Book ID
116065885
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
614 KB
Volume
59
Category
Article
ISSN
0039-128X

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Synthesis of [2,4-3H] 17β-dihydroequilin
Synthesis of [2,4-3H] 17β-dihydroequilin sulfate
✍ Bhagu R. Bhavnani 📂 Article 📅 1994 🏛 John Wiley and Sons 🌐 French ⚖ 269 KB 👁 1 views

## Abstract [2,4‐^3^H] 17β‐dihydroequilin‐3‐sulfate ammonium salt suitable for __in vivo__ pharmacokinetic studies was synthesized from [2,4‐^3^H] equillin. Sulfation of [2,4‐^3^H] equillin with pyridine‐chiorosulfonic acid mixture gave in high yields [2,4‐^3^H] equilin sulfate, which was then redu