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Metabolism Kinetics of Beclomethasone Propionate Esters in Human Lung Homogenates

✍ Scribed by Kuncoro Foe; David J. Cutler; Kenneth F. Brown; J. Paul Seale


Book ID
110251958
Publisher
Springer US
Year
2000
Tongue
English
Weight
152 KB
Volume
17
Category
Article
ISSN
0724-8741

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The kinetics of decomposition of beclomethasone dipropionate (BDP), the 17-monopropionate ester (17-BMP), and beclomethasone (BOH) were characterized in whole human plasma (HP), pH 7.1, and in solutions of 1% human serum albumin (HSA), pH 7.4, and 0.067 M phosphate buffer, pH 7.4 (v=0.17). A reverse