Comparative kinetics of metabolism of beclomethasone propionate esters in human lung homogenates and plasma

Decomposition of beclomethasone propiona

Decomposition of beclomethasone propionate esters in human plasma

✍ Kuncoro Foe; Kenneth F. Brown; John P. Seale 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 182 KB 👁 2 views

The kinetics of decomposition of beclomethasone dipropionate (BDP), the 17-monopropionate ester (17-BMP), and beclomethasone (BOH) were characterized in whole human plasma (HP), pH 7.1, and in solutions of 1% human serum albumin (HSA), pH 7.4, and 0.067 M phosphate buffer, pH 7.4 (v=0.17). A reverse