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Metabolism and hepatotoxicity of N,N-dimethylformamide, N-hydroxymethyl-N-methylformamide, and N-methylformamide in the rat

✍ Scribed by M. Van den Bulcke; M. T. Rosseel; P. Wijnants; W. Buylaert; F. M. Belpaire

Publisher
Springer-Verlag
Year
1994
Tongue
English
Weight
609 KB
Volume
68
Category
Article
ISSN
0340-5761

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Labelled compounds of interest as antitu
Labelled compounds of interest as antitumour agents I: N-methylformamide and N, N-dimethylformamide
✍ Michael D Threadgill; E Nicholas Gate πŸ“‚ Article πŸ“… 1983 πŸ› John Wiley and Sons 🌐 French βš– 189 KB

## Abstract Efficient preparations of N‐methylformamide (an active antitumour agent) have been developed in which the compound is labelled with ^14^C in the formyl group, with ^14^C in the methyl group and with deuterium in the methyl group. N, N‐Dimethyl‐^14^C‐formamide has also been synthesised.