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Metabolic Role of Cytoplasmic Isozymes of 5,10-Methylenetetrahydrofolate Dehydrogenase in Saccharomyces cerevisiae †

✍ Scribed by West, Mary G.; Horne, Donald W.; Appling, Dean R.


Book ID
126187595
Publisher
American Chemical Society
Year
1996
Tongue
English
Weight
414 KB
Volume
35
Category
Article
ISSN
0006-2960

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Crystallization of the NAD-dependent 5,1
✍ Monzingo, Arthur F.; West, Mary G.; Schelp, Elisabeth; Appling, Dean R.; Robertu 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 189 KB

## Saccharomyces cerevisiae possesses three isozymes of 5,lO-methylenetetrahydrofolate dehydrogenase (MTD). The NADdependent enzyme is the first monofunctional form found in eukaryotes. Here we report its crystallization in a form suitable for high-resolution structure. The space group is P4,2,2 w