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Metabolic flux analysis of the sterol pathway in the yeastSaccharomyces cerevisiae

✍ Scribed by Judith Maczek; Stefan Junne; Peter Nowak; Peter Goetz

Publisher
Springer
Year
2006
Tongue
English
Weight
347 KB
Volume
29
Category
Article
ISSN
1615-7605

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The problems of engineering increased flux in metabolic pathways are analyzed in terms of the understanding provided by metabolic control analysis. Overexpression of a single enzyme is unlikely to be effective unless it is known to have a high flux control coefficient, which can be used as an approx