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Metabolic effects of novel N-1-sulfonylpyrimidine derivatives on human colon carcinoma cells

✍ Scribed by Ljubica Glavaš-Obrovac; Ivan Karner; Mario Štefanić; Jelena Kašnar-Šamprec; Biserka Žinić


Book ID
113619836
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
201 KB
Volume
60
Category
Article
ISSN
0014-827X

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The inhibition of arylamine N-acetyltransferase (NAT) activity by ibuprofen was determined in a human colon tumour (adenocarcinoma) cell line. Two assay systems were employed, one with cellular cytosols (9000 g supernatant) and the other with intact colon tumour cell suspensions. The NAT activity in