Metabolic control of energy flux
โ Scribed by Howard E. Morgan
- Book ID
- 119441737
- Publisher
- Elsevier Science
- Year
- 1986
- Tongue
- English
- Weight
- 78 KB
- Volume
- 18
- Category
- Article
- ISSN
- 0022-2828
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Metabolic Control Analysis has invalidated many traditional biochemical concepts of control, in particular the rate-limiting step. However, it has not been used to question the mechanisms by which pathway flux is thought to be controlled, such as the action of allosteric effectors or of covalent mod
The problems of engineering increased flux in metabolic pathways are analyzed in terms of the understanding provided by metabolic control analysis. Overexpression of a single enzyme is unlikely to be effective unless it is known to have a high flux control coefficient, which can be used as an approx