Metabolic control analysis : The effects of high enzyme concentrations
β Scribed by David A. FELL; Herbert M. SAURO
- Book ID
- 115128083
- Publisher
- John Wiley and Sons
- Year
- 1990
- Tongue
- English
- Weight
- 549 KB
- Volume
- 192
- Category
- Article
- ISSN
- 1432-1327
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π SIMILAR VOLUMES
The cellular concentration of enzymes of some major metabolic pathways, such as glycolysis, can approach millimolarity. This concentration of enzyme can catalyze in vitro rates which are 100-fold higher than maximum pathway flux. In an attempt to understand the need for such high enzyme concentratio
The assumption currently considered in the Metabolic Control Theory that velocity of every isolated step is proportional to enzyme concentration, is analysed by considering that in some metabolic systems that condition could not be accomplished. Analysis of the main core of this theory is carried ou