𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Metabolic Control Analysis of the Penicillin Biosynthetic Pathway in a High-Yielding Strain of Penicillium chrysogenum

✍ Scribed by Jens Nielsen; Henrik S. Jørgensen

Book ID
114420661
Publisher
American Institute of Chemical Engineers
Year
1995
Tongue
English
Weight
825 KB
Volume
11
Category
Article
ISSN
8756-7938

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Pathway kinetics and metabolic control a
Pathway kinetics and metabolic control analysis of a high-yielding strain of Penicillium chrysogenum during fed batch cultivations
✍ Pedro de Noronha Pissara; Jens Nielsen; Michael J. Bazin 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 794 KB

A kinetic model representing the pathway for the biosynthesis of penicillin by f . chrysogenum has been developed. The model is capable of describing the flux through the biosynthetic pathway, and model simulations correspond well with measurements of intermediates and end products. One feature of t

Quantitative analysis of Penicillium chr
Quantitative analysis of Penicillium chrysogenum Wis54-1255 transformants overexpressing the penicillin biosynthetic genes
✍ Hanne Aae Theilgaard; Marco A. van den Berg; Céline A. Mulder; Roel A.L. Bovenbe 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 202 KB

The low penicillin-producing, single gene copy strain Wis54-1255 was used to study the effect of overexpressing the penicillin biosynthetic genes in Penicillium chrysogenum. Transformants of Wis54-1255 were obtained with the amdS expression-cassette using the four combinations: pcbAB, pcbC, pcbC-pen

Energetics of growth and penicillin prod
Energetics of growth and penicillin production in a high-producing strain of Penicillium chrysogenum
✍ W. M. vanGulik; M. R. Antoniewicz; W. T. A. M. deLaat; J. L. Vinke; J. J. Heijne 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 127 KB 👁 2 views

The results of a large number of carbon-limited chemostat cultures of Penicillium chrysogenum carried out on glucose, ethanol, and acetate as the growth limiting substrate have been used to obtain an estimation of the adenosine triphosphate (ATP) costs for mycelium growth, penicillin production, and