Metabolic activation of the antidepressant tianeptine: II. in vivo covalent binding and toxicological studies at sublethal doses

Metabolic activation of the tricyclic an

Metabolic activation of the tricyclic antidepressant amineptine—II: Protective role of glutathione against in vitro and in vivo covalent binding

✍ Jean Geneve; Claude Degott; Philippe Letteron; Marina Tinel; Veronique Descatoir 📂 Article 📅 1987 🏛 Elsevier Science 🌐 English ⚖ 790 KB

Bio-Assays for Oxidative Stress Status |

Bio-Assays for Oxidative Stress Status || IN VIVO TOTAL ANTIOXIDANT CAPACITY: COMPARISON OF DIFFERENT ANALYTICAL METHODS11Mention of a trade name, proprietary product, or specific equipment does not constitute a guarantee by the U.S. Department of Agriculture and does not imply its approval to the exclusion of other products that may be suitable.Address correspondence to: R. L. Prior, Ph.D., USDA, ARS, HNRCA, 711 Washington St., Boston, MA 02111, USA; Tel: (617) 556–3311; Fax: (617) 556-3222; E-Mail: [email protected]. Ronald Prior is a Nutritionist and Laboratory Chief of the Phytochemical Laboratory at the Jean Mayer USDA Human Nutrition Research Center on Aging (HNRCA) at Tufts University, Boston, MA. Dr. Prior received his B.S. degree with honors from the University of Nebraska and he received his Ph.D. in Nutrition and Biochemistry from Cornell University in 1972. Dr. Prior has worked with the USDA for more than 20 years.During the past 12 years at the HNRCA, he has been Scientific Program Officer and has directed research activities dealing with the role of flavonoid and other phenolic food components on antioxidant status, their metabolism, and relationships to diseases of aging.Guohua Cao, M.D., Ph.D., is currently a Scientist II at HNRCA. Dr. Cao studied medicine in Nantong Medical College in 1979 and at Nanjing Medical University in 1984. He obtained his Ph.D. in nutritional biochemistry from Beijing Medical University in 1990. Dr. Cao came to the United States in 1991 and worked at NIH where he was instrumental in developing the ORAC method.

✍ PRIOR, RONALD L. 📂 Article 📅 2001 🏛 Elsevier 🌐 English ⚖ 986 KB

This work contains over thirty chapters by leading researchers in the field of oxidative biology, originally presented as articles in an extended Forum in the highly-cited journal, *Free Radical Biology & Medicine*. The papers in this Forum (or Symposium-in-print) spanned seven issues of the journal