Metabolic activation of diethylstilbestr
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H. -G. Neumann; M. Metzler; W. TΓΆpner
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Article
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1977
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Springer-Verlag
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English
β 555 KB
Diethylstilbestrol and trans-4-dimethylaminostilbene are metabolically activated and several of their metabolites are able to react with cellular macromolecules. Some of the problems are discussed which are encountered in linking a particular metabolite with the mutagenic and carcinogenic properties