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Metabolic activation of diethylstilbestrol by stimulated human leukocytes

✍ Scribed by Eastmond, David A.; French, Raymond C.; Ross, David; Smith, Martyn T.


Book ID
123595737
Publisher
Elsevier Science
Year
1987
Tongue
English
Weight
572 KB
Volume
35
Category
Article
ISSN
0304-3835

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Metabolic activation of diethylstilbestr
✍ H. -G. Neumann; M. Metzler; W. TΓΆpner πŸ“‚ Article πŸ“… 1977 πŸ› Springer-Verlag 🌐 English βš– 555 KB

Diethylstilbestrol and trans-4-dimethylaminostilbene are metabolically activated and several of their metabolites are able to react with cellular macromolecules. Some of the problems are discussed which are encountered in linking a particular metabolite with the mutagenic and carcinogenic properties