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Metabolic Actions of Insulin-Like Growth Factor-I in Normal Physiology and Diabetes

✍ Scribed by David R. Clemmons

Book ID
118031517
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
149 KB
Volume
41
Category
Article
ISSN
0889-8529

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## Republic of Germany \* Insulinlike growth factor-I (IGF-I) is of critical importance in the regulation of tissue growth and cellular differentiation (1, 2). In addition to its growthpromoting effects, a rapid insulin-like metabolic activity (e.g., hypoglycemia after intravenous injection) has b

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The acute metabolic actions of insulin-like growth factor I were studied in anaesthetized adult rats and its potency was compared to that of insulin. Following an i.v. bolus injection of insulin-like growth factor I a dose-dependent decrease of blood glucose and serum non-esterified fatty acid conce