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Meta-iodobenzylguanidine (MIBG) inhibits malate and succinate driven mitochondrial ATP synthesis in the human neuroblastoma cell line SK-N-BE(2c)

✍ Scribed by J. Cornelissen; R.J.A. Wanders; C. Van den Bogert; A.B.P. Van Kuilenburg; L. Elzinga; P.A. Voǔte; A.H. Van Gennip

Book ID
116166227
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
623 KB
Volume
31
Category
Article
ISSN
0959-8049

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We report the effects of meta-iodobenzylguanidine (MIBG), a neuroblastoma-seeking agent, on cell proliferation and several oxidative stress-related parameters in the human neuroblastoma cell line SK-N-BE(2c). MIBG inhibited the proliferation of this cell line in micromolar concentrations. Measuremen