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Meta-analysis shows association between the tryptophan hydroxylase (TPH) gene and schizophrenia

✍ Scribed by Dawei Li; Lin He

Book ID: 106134385
Publisher: Springer
Year: 2006
Tongue: English
Weight: 373 KB
Volume: 120
Category: Article
ISSN: 0340-6717
DOI: 10.1007/s00439-006-0190-5

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## Abstract Genes encoding proteins involved in serotonergic metabolism are major candidates in association studies of suicidal behavior. The tryptophan hydroxylase (TPH) gene, which codes for the rate‐limiting enzyme of serotonin biosynthesis, is a major candidate gene and has been extensively stu