The relationship between the genetically defined intensity of intermale aggression and the activity of brain tryptophan hydroxylase (TPH) has been studied in inbred mice. No association between the enzyme activity and the percentage of aggressive mice (reflecting the predisposition to aggressive rea
β¦ LIBER β¦
Possible association between autism and variants in the brain-expressed tryptophan hydroxylase gene (TPH2)
β Scribed by Hilary Coon; Diane Dunn; Janet Lainhart; Judith Miller; Cindy Hamil; Agatino Battaglia; Raffaella Tancredi; Mark F. Leppert; Robert Weiss; William McMahon
- Publisher
- John Wiley and Sons
- Year
- 2005
- Tongue
- English
- Weight
- 71 KB
- Volume
- 135B
- Category
- Article
- ISSN
- 1552-4841
No coin nor oath required. For personal study only.
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## Abstract Previous studies have suggested that the serotonergic (5βHT) system might be involved in the development of Attentionβdeficit hyperactivity disorder (ADHD). ADHD is frequently characterized by aggressive and impulsive behavior, a major symptom associated with reduction in serotonergic f