Meta-analysis of association of insertion/deletion polymorphism of angiotensin I-converting enzyme gene with diabetic nephropathy and retinopathy
β Scribed by T. Fujisawa; H. Ikegami; Y. Kawaguchi; Y. Hamada; H. Ueda; M. Shintani; M. Fukuda; T. Ogihara
- Publisher
- Springer
- Year
- 1998
- Tongue
- English
- Weight
- 220 KB
- Volume
- 41
- Category
- Article
- ISSN
- 0012-186X
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An insertion(I)/deletion(D) polymorphism in the angiotensin I-converting enzyme (ACE) gene seems to be associated with clinical heart disease in patients with diabetes mellitus. It is not known whether increased atherosclerosis or other factors among individuals with certain ACE-gene subtypes form t
A recent Japanese study on the angiotensin I converting enzyme gene (ACE) insertion/ deletion polymorphism reported that both the D allele (P < 0.02) and the DD genotype (P < 0.002) were significantly more frequent in affective disorder cases than in controls [Arinami et al., 1996: Biol Psychiatry 4