Mercury Uptake by LLC-PK1Cells: Dependence on Temperature and Membrane Potential
β Scribed by Tetsuya Endo; Osamu Kimura; Masakatsu Sakata; Zahir A. Shaikh
- Book ID
- 112266502
- Publisher
- Elsevier Science
- Year
- 1997
- Tongue
- English
- Weight
- 112 KB
- Volume
- 146
- Category
- Article
- ISSN
- 0041-008X
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π SIMILAR VOLUMES
## Abstract Cultured pig kidney cells designated LLCβPK~1~, previously shown to acquire Na ^+^ βdependent concentrative transport of hexoses as the cells become growth arrested, also show Na ^+^ βdependent concentrative uptake of the amino acid analogs Ξ±βaminoisobutyric acid (AIB) and (methyl) meAI
Cyclosporine A (CSA) is an effective immunosuppressant, but side effects such as renal toxicity can limit its therapeutic use. The current studies investigate the effects of lipoproteins on CSA-induced renal toxicity in the pig epithelial cell line LLC-PK 1 . Protein synthesis and tritiated CSA were