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Mercury exposure does not elevate systolic blood pressure in normotensive rats

✍ Scribed by Hiroki Takahashi; Hiroko Nomiyama; Kazuo Nomiyama

Publisher: John Wiley and Sons
Year: 2000
Tongue: English
Weight: 122 KB
Volume: 13
Category: Article
ISSN: 0896-548X
DOI: 10.1002/(sici)1520-670x(2000)13:2<239::aid-jtra7>3.0.co;2-7

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✦ Synopsis

Wistar-Kyoto rats are the original normotensive strain of the spontaneously hypertensive rat (SHR). Fifty male Wistar-Kyoto rats were fed 15 g/day of pelleted food containing mercuric chloride (HgCl 2 ) at dose levels of 0, 1, 3, 10, or 30 g/g over a period of 21 weeks. No dose-related difference in blood pressure was observed in normotensive rats of the Wistar-Kyoto strain fed mercuric chloride.

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