Meperidine and normeperidine metabolism in the rhesus monkey
โ Scribed by John C. Morrison; Stavros G. Douvas; Philip G. Rhodes; Russell J. Christie; Edsel T. Bucovaz; Winfred L. Wiser
- Book ID
- 118887813
- Publisher
- Elsevier Science
- Year
- 1984
- Tongue
- English
- Weight
- 417 KB
- Volume
- 22
- Category
- Article
- ISSN
- 0020-7292
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๐ SIMILAR VOLUMES
A GLC procedure for the determination of meperidinic and normeperidinic acids in human urine is described. After the extraction of any interfering meperidine or normeperidine, the urine samples are dried and the acids are reesterified using ethanol-sulfuric acid. The resulting meperidine and normepe
The effects of naloxone and 5-hydroxytryptophan (5-HTP) pretreatment on convulsions induced by meperidine and normeperidine were studied in male Swiss-Webster mice. The CD50 (95% confidence limits) was found to be 17.5 mg/kg (15.6-19.6) for meperidine and 38.0 mglkg (36.2-39.9) for normeperidine adm