Menschutkin reaction stereoselectivities of nicotine and related compounds
โ Scribed by Jeffrey I. Seeman; Henry V. Secor; Jerry F. Whidby; Ronald L. Bassfield
- Publisher
- Elsevier Science
- Year
- 1978
- Tongue
- French
- Weight
- 242 KB
- Volume
- 19
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
โฆ Synopsis
Recently
we reported that iodomethylation of nicotine (2) led to the formaof N'-methylnicotinium iodide (5, n=5) and N-methylnicotinium iodide (6,
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## Stereoselectivity has been demonstrated in reactions of various fluorinated compounds, fog example, the synthesis of cisand rrans-PhZTeFq, the synthesis of cisand tmns-FZTePhjCl, or selective fluorine exchange of non-equivalent fluorines in mer-PhgTeF3 and cis-F2TePh,CI
## Abstract The potential of ^13^C NMR techniques for studies of nicotine metabolism has been investigated by acquisition and assignment of ^13^C NMR spectra of nicotine, its metabolites and some related compounds. It is shown that Cโ2โฒ of nicotine would be the best site for ^13^C labelling when us