Involvement of inducible costimulator in
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Andreas Hutloff; Kerstin Büchner; Karin Reiter; Hans J. Baelde; Marcus Odendahl;
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Article
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2004
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John Wiley and Sons
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English
⚖ 281 KB
👁 1 views
## Abstract ## Objective In systemic lupus erythematosus (SLE), the increased generation of memory B cells and plasma cells leads to autoimmune hypergammaglobulinemia and destructive immunoglobulin deposits in the kidneys. We undertook this study to determine the biologic mechanism driving this ov