Immunological memory: SAPping B-cell memory
โ Scribed by Bell, Elaine
- Book ID
- 109953791
- Publisher
- Nature Publishing Group
- Year
- 2003
- Tongue
- English
- Weight
- 210 KB
- Volume
- 3
- Category
- Article
- ISSN
- 1474-1741
- DOI
- 10.1038/nri1009
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๐ SIMILAR VOLUMES
Most of the antigen-specific T and B cells participating in the primary immune response are rapidly eliminated, but some of the cells survive and become long-lived memory cells. There have been a number of recent developments on the features and functions of memory cells.
CD4 and CD8 T lymphocytes can be further subdivided using antibodies to isoforms of CD45 with restricted cellular distributions. These further subsets, detected in man, rodents and sheep, differ in surface phenotypes, rate of cycling, migration and response to recall antigens. Their lineage relation