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Membrane-type 1 matrix metalloproteinase-mediated progelatinase A activation in non-tumorigenic and tumorigenic human keratinocytes

✍ Scribed by Baumann, P.


Book ID
111724389
Publisher
Nature Publishing Group
Year
2000
Tongue
English
Weight
130 KB
Volume
83
Category
Article
ISSN
0007-0920

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Matrix metalloproteinases (MMPs) and integrins have been implicated in a variety of processes involved in tumor progression. To evaluate the individual roles of integrin alphavbeta3 and membrane-type 1 matrix metalloproteinase (MT1-MMP), as well as the effects of their joint expression on tumor cell