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Cell Type-Specific Involvement of Furin in Membrane Type 1 Matrix Metalloproteinase-Mediated Progelatinase A Activation

✍ Scribed by TAKASHI SATO; TAKAYUKI KONDO; MOTOHARU SEIKI; AKIRA ITO


Book ID
111395094
Publisher
John Wiley and Sons
Year
1999
Tongue
English
Weight
493 KB
Volume
878
Category
Article
ISSN
0890-6564

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Involvement of membrane type 1-matrix me
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## Abstract An advanced glycation end products (AGE)/a receptor for AGE (RAGE) axis plays a key role in diabetic vascular complications. Membrane type 1‐matrix metalloproteinase (MT1‐MMP) has been shown to function not only as a proteolytic enzyme but also as a signaling molecule. In this study, we