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Membrane receptor stripping confirms the association between ebv receptors and complement receptors on the surface of human b lymphoma lines

✍ Scribed by Eitan Yefenof; George Klein

Publisher
John Wiley and Sons
Year
1977
Tongue
French
Weight
434 KB
Volume
20
Category
Article
ISSN
0020-7136

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✦ Synopsis

Abstract

Complement (C3) receptors, EBV receptors, Fc receptors, membrane IgM and beta~2~microglobulin (β~2~m) were individually stripped from the surface of human B lymphoma lines. The cells were subsequently tested for their ability to absorb infectious EB virus. Stripping of Fc receptors, IgM and β~2~m did not reduce EBV absorption. Stripping of either EBV receptors or C3 receptors eliminated or drastically reduced EBV‐absorptive capacity. The results confirm the distinctive association between EBV receptors and C3 receptors on human lymphoma cells.

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