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Membrane Insertion Scanning of the Human Ileal Sodium/Bile Acid Co-transporter †

✍ Scribed by Hallén, Stefan; Brändén, Magnus; Dawson, Paul A.; Sachs, George

Book ID
127342240
Publisher
American Chemical Society
Year
1999
Tongue
English
Weight
259 KB
Volume
38
Category
Article
ISSN
0006-2960

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Ileal expression of the apical sodium-dependent bile acid transporter (ASBT) in the rat is unaffected by bile salts, yet in the mouse it is under negative-feedback regulation. The bile acid responsiveness of human ASBT is unknown. The human ASBT promoter linked to a luciferase reporter was studied i