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Isolation, expression, and characterization of a human ileal sodium-dependent bile acid transporter

✍ Scribed by Behbod, F.; Loose-Mitchell, D.

Book ID
122916685
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
184 KB
Volume
114
Category
Article
ISSN
0016-5085

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Ileal expression of the apical sodium-dependent bile acid transporter (ASBT) in the rat is unaffected by bile salts, yet in the mouse it is under negative-feedback regulation. The bile acid responsiveness of human ASBT is unknown. The human ASBT promoter linked to a luciferase reporter was studied i