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Melkersson–Rosenthal syndrome in childhood: a challenge in differential diagnosis and treatment

✍ Scribed by P.E. Ziem; C. Pfrommer; S. Goerdt; C.E. Orfanos; U. Blume-Peytavi

Publisher
John Wiley and Sons
Year
2000
Tongue
English
Weight
248 KB
Volume
143
Category
Article
ISSN
0007-0963

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✦ Synopsis

Facial palsy and orofacial swelling in childhood represent a challenge in differential diagnosis for paediatricians and dermatologists. One possible entity, Melkersson-Rosenthal syndrome (MRS), is a rarity in childhood. We describe a 9-year-old girl with the diagnosis of MRS who had episodic swelling of the upper lip and complete peripheral facial palsy, associated with herpes and recurrent bacterial infections. Therapeutic options for MRS in childhood are limited. Our patient benefited from a 2-month course of prednisolone 1 mg kg(-1) daily. We review previously published cases of MRS in childhood, and discuss the differential diagnosis of orofacial swelling and facial palsy as well as treatment options in children.

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