Cerebriform nodular amelanotic metastases of malignant melanoma: a challenge in differential diagnosis of a rare variant

✍ Scribed by A. Assmann; B. Farthmann; O. Burkhardt; E. Dippel; C.E. Orfanos; U. Blume-Peytavi

• Publisher: John Wiley and Sons
• Year: 2000
• Tongue: English
• Weight: 387 KB
• Volume: 142
• Category: Article
• ISSN: 0007-0963
• DOI: 10.1046/j.1365-2133.2000.03372.x

✦ Synopsis

Abstract

High variability of the clinical appearance of malignant melanoma (MM) and its metastases render the differential diagnosis of solid amelanotic tumours difficult. We report a 71-year-old woman with several unusual cutaneous tumours of cerebriform morphology, suggesting skin metastases from occult internal cancer. Histopathological findings and thorough investigations, however, revealed a late-stage metastatic MM. We discuss the differential diagnosis of skin metastases of various origin and underline the difficulties for early detection of MM.