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Melatonin treatment induces interplay of apoptosis, autophagy, and senescence in human colorectal cancer cells

✍ Scribed by Hong, Yunkyung; Won, Jinyoung; Lee, Youngjeon; Lee, Seunghoon; Park, Kanghui; Chang, Kyu-Tae; Hong, Yonggeun


Book ID
126973293
Publisher
John Wiley and Sons
Year
2014
Tongue
English
Weight
977 KB
Volume
56
Category
Article
ISSN
0742-3098

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## Abstract Vascular endothelial growth factor (VEGF) inhibitors, such as bevacizumab, have improved outcomes in metastatic colorectal cancer (CRC). Recent studies have suggested that VEGF can delay the onset of cellular senescence in human endothelial cells. As VEGF receptors are known to be upreg