Ursolic acid induces cell death and modulates autophagy through JNK pathway in apoptosis-resistant colorectal cancer cells
β Scribed by Xavier, Cristina P.R.; Lima, Cristovao F.; Pedro, Dalila F.N.; Wilson, Jonathan M.; Kristiansen, Karsten; Pereira-Wilson, Cristina
- Book ID
- 122721210
- Publisher
- Elsevier Science
- Year
- 2013
- Tongue
- English
- Weight
- 898 KB
- Volume
- 24
- Category
- Article
- ISSN
- 0955-2863
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## Abstract Androgenβindependent prostate cancers express high levels of Bclβ2, and this overβexpression of Bclβ2 protects prostate cancer cells from undergoing apoptosis. Ursolic acid (UA) has demonstrated an antiβproliferative effect in various tumor types. The aim of this study is to evaluate th