Melatonin prevents experimental liver cirrhosis induced by thioacetamide in rats
✍ Scribed by Adolfo Cruz; Francisco J. Padillo; Eva Torres; Carmen M. Navarrete; Juan R. Muñoz-Castañeda; Francisco J. Caballero; Javier Briceño; Trinidad Marchal; Isaac Túnez; Pedro Montilla; Carlos Pera; Jordi Muntané
- Book ID
- 111264234
- Publisher
- John Wiley and Sons
- Year
- 2005
- Tongue
- English
- Weight
- 585 KB
- Volume
- 39
- Category
- Article
- ISSN
- 0742-3098
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## Abstract The aim of the study was to analyze the impact of melatonin on brain oxidative stress in experimental biliary obstruction. Cholestasis was done by a double ligature and section of the extrahepatic biliary duct. Melatonin was injected intraperitoneally (500 μg/kg/day). Malondialdehyde (M