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Melatonin administration increases the affinity of D2 dopamine receptors in the rat striatum

โœ Scribed by Anwar Hamdi

Book ID
117176720
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
467 KB
Volume
63
Category
Article
ISSN
0024-3205

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Chronic haloperidol administration incre
Chronic haloperidol administration increases the density of D2 dopamine receptors in the medial prefrontal cortex of the rat
โœ A. John MacLennan; Stella Atmadja; Nancy Lee; H. C. Fibiger ๐Ÿ“‚ Article ๐Ÿ“… 1988 ๐Ÿ› Springer ๐ŸŒ English โš– 299 KB

Rats received haloperidol (1.3-1.5 mg/kg/day) via their drinking water for 21 weeks. At the end of this period the density of D2 dopamine receptors and their affinity for [3H]-spiperone were measured in the striatum and medial prefrontal cortex. The chronic haloperidol treatment increased the densit