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Melanocyte stimulating hormone peptides inhibit TNF-α signaling in human dermal fibroblast cells

✍ Scribed by R.P. Hill; S. MacNeil; J.W. Haycock


Book ID
116830813
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
452 KB
Volume
27
Category
Article
ISSN
0196-9781

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✍ Hedley; Gawkrodger; Weetman; Morandini; Boeynaems; Ghanem; Mac Neil 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 593 KB

alpha-Melanocyte stimulating hormone (alpha-MSH) was found significantly to reduce tumour necrosis factor-alpha (TNF-alpha) stimulated upregulation of intercellular adhesion molecule-1 (ICAM-1) in normal adult cutaneous melanocytes. The maximum inhibitory response to alpha-MSH was obtained at around