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Megestrol acetate reverses multidrug resistance and interacts with P-glycoprotein

✍ Scribed by Gini F. Fleming; Jacqueline M. Amato; Michael Agresti; Ahmad R. Safa


Publisher
Springer
Year
1992
Tongue
English
Weight
699 KB
Volume
29
Category
Article
ISSN
0344-5704

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## Abstract Twenty‐four fresh tumors of gastric carcinoma were assessed by flow cytometric detection of P‐glycoprotein (P‐gp) using monoclonal antibody C219. Eight patients were P‐gp positive. Differentiated gastric carcinomas contained significantly higher concentrations of P‐gp positive. Incidenc