<p>Medullary Thyroid Carcinoma is a rare thyroid tumor originating from neural crest cells, the C-cell that implies several special features, secretion of different neuroendocrine markers, association with other endocrine tumors and familial appearance. The familial variant of medullary thyroid carc
Medullary Thyroid Cancer
β Scribed by Tracy S. Wang, Douglas B. Evans (eds.)
- Publisher
- Springer International Publishing
- Year
- 2016
- Tongue
- English
- Leaves
- 206
- Edition
- 1
- Category
- Library
No coin nor oath required. For personal study only.
β¦ Synopsis
This text provides a comprehensive, contemporary review of this disease and serves as an important resource for clinicians and researchers with an interest in medullary thyroid cancer. The book reviews the initial management of the patient with thyroid nodules, including risk factors, appropriate genetic evaluation of suspected/known medullary thyroid cancer, and appropriate screening for diseases associated with inherited forms of medullary thyroid cancer, including primary hyperparathyroidism and pheochromocytomas. It includes an in-depth discussion of the optimal surgical management of patients with sporadic and inherited disease, those with locoregional metastases, distant metastases, and recurrent medullary thyroid cancer. The long-term follow-up and management of patients with medullary thyroid cancer is highlighted.
Medullary Thyroid Cancer will serve as a useful resource for all providers and researchers interested in this relatively rare and challenging malignancy. It highlights recent guidelines for the management of patients with medullary thyroid cancer and discusses controversies within the literature. All chapters are written by experts in the field and incorporate multiple disciplines, including Surgery (Endocrine Surgery, General Surgery, and Otolaryngology), Endocrinology, Radiology, Medical Oncology and Genetic Counseling.
β¦ Table of Contents
Front Matter....Pages i-xi
History and Epidemiology....Pages 1-16
Initial Evaluation and Diagnosis of Medullary Thyroid Carcinoma....Pages 17-24
The Physiology of Serum Calcitonin and Carcinoembryonic Antigen in Medullary Thyroid Cancer....Pages 25-31
Cytology and Pathology: Pitfalls and Challenges....Pages 33-46
Molecular Mechanisms of Disease: The RET Proto-oncogene....Pages 47-63
Genetic Evaluation of the Patient with Medullary Thyroid Cancer....Pages 65-75
Preoperative Evaluation of the Patient with Medullary Thyroid Cancer....Pages 77-83
Inherited Medullary Thyroid Carcinoma: Indications and Technique of Early Thyroidectomy ....Pages 85-94
Surgical Management of Inherited MTC: Therapeutic Thyroidectomy....Pages 95-102
Surgical Management of Parathyroid and Adrenal Glands in Inherited Medullary Thyroid Carcinoma....Pages 103-114
Surgical Management of Sporadic Medullary Thyroid Cancer (Extent of Thyroid Resection and the Role of Central and Lateral Neck Dissection)....Pages 115-126
Surgical Management of Invasive Medullary Thyroid Carcinoma....Pages 127-136
Importance of Thyroid Hormone Replacement Therapy in Patients with Medullary Thyroid Cancer....Pages 137-149
Medullary Thyroid Cancer: The Role of External Beam Therapy....Pages 151-155
Management of Patients with Metastatic Medullary Thyroid Carcinoma: The Role for Systemic Therapy....Pages 157-164
Ablative Therapies of the Liver and Bone in Medullary Thyroid Cancer....Pages 165-171
Emerging Therapies for Progressive Metastatic Medullary Thyroid Cancer....Pages 173-181
Follow-Up and Surveillance of Patients with Medullary Thyroid Carcinoma....Pages 183-188
Surgical Management of Recurrent Medullary Thyroid Cancer....Pages 189-197
Back Matter....Pages 199-205
β¦ Subjects
General Surgery;Endocrinology;Surgical Oncology
π SIMILAR VOLUMES
<p>This book offers a comprehensive overview of medullary thyroid carcinoma, both in the more common sporadic form and in the familial form, multiple endocrine neoplasia (MEN) types 2A and 2B. The coverage includes, but is not limited to, molecular biology and genetics, pathology, clinical presentat
<p><p>The American Cancer Society recently estimated that about 45,000 new cases of thyroid cancer will be diagnosed in the United States, with three-quarters occurring in women. The overall 5-year survival rate is about 97%, making it one of the least lethal cancers. We are experiencing an epidemic
<p>One of the main reasons for publishing this second edition of βT- roid Cancerβ is the fact that the first edition has sold out. Furth- more, during the 4 years following the publication of the first edition in 2001, some progress, mainly in the basic sciences (molecular biology), has been made. T
<p><p>The American Cancer Society recently estimated that about 45,000 new cases of thyroid cancer will be diagnosed in the United States, with three-quarters occurring in women. The overall 5-year survival rate is about 97%, making it one of the least lethal cancers. We are experiencing an epidemic