Medium Effect on the Rotational Isomerism in 1,3,5-Triacetylbenzene
✍ Scribed by Aleksandra Konopacka; Joanna Pająk; Guido Maes; Zbigniew Pawełka
- Publisher
- Springer Vienna
- Year
- 2007
- Tongue
- English
- Weight
- 283 KB
- Volume
- 138
- Category
- Article
- ISSN
- 0026-9247
No coin nor oath required. For personal study only.
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Various valuable publications on topographical and electronic aspects of the structure-activity relationships (SAR) of 5-aryl-l,4-benzodiazepin-2-ones are known"5). However, to our surprise we found, that in all these reports conformational preferences of the 5-aryl ring were almost totally ignored.
## Abstract A ^1^H dynamic NMR study of the hindered rotation in 5‐amino‐6‐(__N__‐methylformamido)‐__as__‐triazin‐3(2__H__)‐one was conducted. Signals for two rotamers were observed and their proton chemical shifts were assigned. It was found that the rotamer in which the __as__‐triazine ring is __