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Mediated efflux of IgG molecules from brain to blood across the blood–brain barrier

✍ Scribed by Yun Zhang; William M Pardridge


Book ID
114137318
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
239 KB
Volume
114
Category
Article
ISSN
0165-5728

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In this study, we investigated the mechanism of the blood -brain barrier (BBB) transport of bunitrolol (BTL), as a model of i-blocker, in vivo and in vitro. In order to define the contribution of P-glycoprotein (P-gp) to the active efflux of BTL from brain to blood, we examined the in vivo brain dis