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Media replenishment: A tool for the analysis of high-cell density perfusion systems

โœ Scribed by Mina D. Mahadevan; John A. Klimkowsky; Yashwant M. Deo


Book ID
104930219
Publisher
Springer
Year
1994
Tongue
English
Weight
464 KB
Volume
14
Category
Article
ISSN
0920-9069

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Temperature is a key environmental variable whose potential in animal cell fermentor optimization is not yet fully utilized. The scarce literature data suggests that reduced fermentor temperature results in an improved viability and shear resistance, higher cell density and titer in batch cultures,