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MeCP2 preferentially binds to methylated linker DNA in the absence of the terminal tail of histone H3 and independently of histone acetylation

✍ Scribed by Toyotaka Ishibashi; Anita A. Thambirajah; Juan Ausió

Book ID
113620692
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
693 KB
Volume
582
Category
Article
ISSN
0014-5793

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## Objective: To assess the role of antibodies to histones h2a, h2b, and anti-double-stranded dna which form (h2a-h2b)-dna complexes in patients with scleroderma-related disorders. ## Methods: Antihistone antibodies were measured, by enzyme immunoassay, in 26 patients with scleroderma-related dis