MeCP2 and promoter methylation cooperatively regulate E-cadherin gene expression in colorectal carcinoma
β Scribed by Agus Darwanto; Riko Kitazawa; Sakan Maeda; Sohei Kitazawa
- Book ID
- 108582288
- Publisher
- John Wiley and Sons
- Year
- 2003
- Tongue
- English
- Weight
- 805 KB
- Volume
- 94
- Category
- Article
- ISSN
- 1347-9032
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
CpG methylation in the promoter region has been shown to be important in the regulation of genes implicated in malignant transformation. The present study was designed to test the hypothesis that CpG methylation of the promoter region of the E-cadherin gene may inactivate its expression in renal cel
## Abstract The __FES__ locus encodes a unique nonreceptor proteinβtyrosine kinase (FES) traditionally viewed as a protoβoncogene but more recently implicated as a tumor suppressor in colorectal cancer (CRC). Recent studies have demonstrated that while FES is expressed in normal colonic epithelium,