CpG methylation in the promoter region has been shown to be important in the regulation of genes implicated in malignant transformation. The present study was designed to test the hypothesis that CpG methylation of the promoter region of the E-cadherin gene may inactivate its expression in renal cel
β¦ LIBER β¦
DNA methyltransferase 1 expression and promoter methylation of E-cadherin in mucoepidermoid carcinoma
β Scribed by Yi-Shing Shieh; Shine-Gwo Shiah; Hao-Hsuan Jeng; Herng-Sheng Lee; Cheng-Wen Wu; Long-Chang Chang
- Publisher
- John Wiley and Sons
- Year
- 2005
- Tongue
- English
- Weight
- 372 KB
- Volume
- 104
- Category
- Article
- ISSN
- 0008-543X
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## Abstract Promoter hypermethylation of various tumorβrelated genes is extremely frequent in EpsteinβBarr virus (EBV)βassociated gastric carcinoma (EBVaGC). To investigate the significance of the promoter methylation in EBVaGC, we focused on one of the important proteins in the carcinogenesis of t