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Mechanosensitive induction of apoptosis in fibroblasts is regulated by thrombospondin-1 and integrin associated protein (CD47)

✍ Scribed by R. Graf; M. Freyberg; D. Kaiser; P. Friedl


Book ID
110397805
Publisher
Springer
Year
2002
Tongue
English
Weight
238 KB
Volume
7
Category
Article
ISSN
1360-8185

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In the present study, we investigated whether the activation of protein kinase C (PKC) and extracellular signal-regulated kinase 1/2 (Erk1/2) are involved in the induction of MMP-9 in lipopolysaccharide (LPS)-stimulated primary astrocytes. The expression of MMP-9 but not MMP-2 was increased by LPS.