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Mechanistic Studies on Thiaminase I: Identification of the Product of Thiamin Degradation in the Absence of the Nucleophilic Cosubstrate

โœ Scribed by Min Wu; Elizabeth T. Papish; Tadhg P. Begley

Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
46 KB
Volume
28
Category
Article
ISSN
0045-2068

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โœฆ Synopsis

Thiaminase I catalyzes the decomposition of thiamin under basic conditions in the absence of the nucleophilic cosubstrate. The product of this reaction was identified as the adduct resulting from the displacement of the thiazole moiety of thiamin by the ring opened form of thiamin.

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