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Mechanistic and pharmacodynamic studies of a 25-hydroxyvitamin D3 derivative in prostate cancer cells

โœ Scribed by James R. Lambert; Christian D. Young; Kelly S. Persons; Rahul Ray


Book ID
116295323
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
216 KB
Volume
361
Category
Article
ISSN
0006-291X

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โœ Narasimha Swamy; Kelly S. Persons; Tai C. Chen; Rahul Ray ๐Ÿ“‚ Article ๐Ÿ“… 2003 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 219 KB

In this report we describe that 1,25(OH)(2)D(3)-3-BE, a VDR-affinity labeling analog of 1,25(OH)(2)D(3), showed strong and dose-dependent growth-inhibitory effect in several epithelial cells, i.e., keratinocytes (primary cells), MCF-7 breast cancer, PC-3, and LNCaP prostate cancer and PZ-HPV-7 immor